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The Department of Health and Social Care said 44,220 people had died in hospitals, care homes and the wider community after testing positive for coronavirus in the UK as of 5pm on Saturday.
This is up by 22 from 44,198 the previous day.
The Government figures do not include all deaths involving Covid-19 across the UK, which are thought to have passed 55,000.
The DHSC also said that in the 24-hour period up to 9am on Sunday, there were 516 positive results. Overall, a total of 285,416 cases have been confirmed.
It comes as the nation clapped at 5pm on Sunday as a way of saying thank you to NHS staff who have worked throughout the coronavirus pandemic.
The initiative follows the success of the weekly Clap for Carers, and it is hoped the applause will become an annual tradition.
Prime Minister Boris Johnson met NHS workers in the Number 10 garden on Sunday afternoon, while public buildings including the Royal Albert Hall, Blackpool Tower and the Shard have been lit up blue in tribute to the health service.
Speaking at a Downing Street press conference on Friday, Mr Johnson urged the public to clap for “those who have worked tirelessly and selflessly to help the nation get through this pandemic”.
