With two games to play, it’s testament to the Blades’ exceptional first season back in the Premier League that they still have a chance of securing European football.
Everton, on the other hand, are facing a complete rebuild under Carlo Ancelotti and are set for a bottom-half finish in the league.
Neither team won their last outing, with the Toffees needing a late equaliser to avoid defeat at home to relegation-threatened Aston Villa.
Here’s all you need to know about the game.
When is it and what time is kick-off?
The match will begin at 6pm on Monday 20 July at Bramall Lane.
How can I watch it online and on TV?
The match will be broadcast live on Amazon Prime Video and streamed live on Twitch.
Sheffield United are likely to be without Leon Clarke and Luke Freeman, but otherwise have a clean bill of health.
Everton will be without long-term absentees Jean-Philippe Gbamin and Fabian Delph, but Mason Holgate may return. Yerry Mina remains a doubt.
Sheffield United: Henderson; Basham, Egan, O’Connell; Baldock, Fleck, Norwood, Berge, Stevens; McBurnie, Mousset.
Everton: Pickford; Coleman, Branthwaite, Keane, Digne; Walcott, Davies, Gomes, Gordon; Richarlison, Calvert-Lewin.
What are the odds?
Sheffield United: 6/5
Everton are having a woeful end to the season and showing Ancelotti just what a big rebuilding job he has to do. The Blades have far more to play for and need a response after defeat to Leicester.
Sheffield United 2-0 Everton