These spots eventually form scabs that will fall off later.
Cases are normally limited to central and western African countries; usually in regions close to tropical rainforests.
Before the two cases detected in Wales, the last UK incidence was reported in England in December 2019, the virus first appeared in the UK in 2018.
It can be difficult to confirm if it is monkeypox as it is similar to other infections such as chickenpox, so it is often confused.