Taylor Swift beat the late singer during Sunday’s ceremony, during which she picked up six new awards.
This brings her total to 29, surpassing Jackson’s 24 wins.
Swift notably won the Artist of the Year award on Sunday, as well as Favourite Pop/Rock Album.
The latter was the one that enabled her to initially tie with Jackson before scoring additional wins.
Swift performed a medley of her hits before accepting the Artist of the Decade award, which came amid her ongoing conflict with music executive Scooter Braun.
The singer said the last year had “the most amazing times and some of the hardest things I have gone through in my life,” but that she felt lucky.
On Sunday, she also collected the Favourite Music Video, Favourite Pop/Rock Female Artist, and Favourite Adult Contemporary Artist awards.
Swift won her first American Music Award in 2008 and collected more trophies in 2009, 2010, 2011, 2012, 2013, 2014, 2015, and 2018.