He and the Transformers actor first starting dating in 2004, becoming engaged two years later.
They wed in Hawaii in 2010 and have three sons together, seven-year-old Noah, six-year-old Bodhi and three-year-old Journey.
While speaking about his split from the 34-year-old, Green said the couple have been “trying to sort of be apart” since the end of 2019 so they can “figure out what life is now”.
“I will always love her,” the 46-year-old said. “And I know she will always love me and I know as far as a family what we built is really cool and really special.”
Green added that they would still go on holiday together as a family, sounding emotional as he described the close connection he and Fox have forged over the years.
“It sucks when life changes and something that you’re used to, that you’ve been doing for 15 years, you try and not get rid of but you change,” he said.
“There’s the unknown aspect, there’s that pit in my stomach. I really don’t want Megan and I to be at odds. She’s been my best friend for 15 years and I don’t want to lose that.”
During the podcast, Green also mentioned Fox’s friendship with rapper Machine Gun Kelly, whose real name is Colson Baker.
In light of the photographs that recently emerged of Fox and Baker spending time together, Green said: “They’re friends at this point.”
“She met this guy, Colson, on set, on this film she’s working on. I’ve never met him, goes by Machine Gun Kelly. But Megan and I have talked about him,” the actor stated.
“They’re friends at this point. From what she’s expressed he’s a really just nice, genuine guy.”
Green added that Fox has “always had really good judgement”, and that he doesn’t want people to think of her or Machine Gun Kelly in a negative light.
“I trust her judgement, she’s always had really good judgement,” he said.
“I don’t want people to think her or he are villains or that I was a victim in any way.”