Manchester United travel to PSG 2-0 down after a disappointing first leg at Old Trafford last month.
Presnel Kimpembe and Kylian Mbappe ensured the French giants took a lead home for the second leg.
No team has ever progressed in the knockout stages after losing at home by two or more goals in the first leg.
And Express Sport is on hand to reveal which United stars could miss the first leg of the quarter-finals should the Red Devils progress.
United have four stars who are one yellow card away from a one-game suspension.
Antonio Valencia, Ashley Young, Ander Herrera and Nemanja Matic could miss the first leg of the quarter-finals if they are booked on Wednesday night.
However, it shouldn’t be a problem for Valencia, Matic and Herrera, who are set to miss Wednesday’s clash through injury.
United are already without Paul Pogba for the PSG clash after the France international was sent off in the first leg.
Many are writing off the Red Devils, with history pointing to PSG progressing into the quarter-finals.
However, United boss Ole Gunnar Solskjaer has urged his team to create history at the Parc Des Princes.
“Goals always change games. We’ve got to get the first goal and then anything can happen,” Solskjaer said.
“Football is a technical and tactical game but it’s also a mental game.
“If we get the first one we would start believing more and then they might start doubting themselves.
“It’s never mission impossible. It’s just more difficult.
“Everyone knows we can do it. In the Champions League in the last few years there have been so many examples of teams that can change results like this.
“When nobody believes in you there is always that bit of character in yourself that you want to show.
“Making history is not the motivation. The motivation is going through. These players aren’t used to losing.”
