Both sides have experienced indifferent form so far this season, and each come into the clash having won just two of the last five league games.
Barca remain joint-top with rivals Real Madrid though, and have a 12-point advantage over Valencia, who are battling with the chasing pack down in seventh.
The match is due to be screened live on LaLigaTV as part of a new broadcasting deal, which launched on January 13.
Here’s how you can tune in….
When is the match?
Valencia and Barcelona meet for their La Liga clash on Saturday January 26.
Kick-off is scheduled for 3pm local time [2pm UK time].
Where is the match?
Valencia play host for this one, as they welcome Barca to the Mestalla.
Los Ches came away from the return fixture back in September without anything to show for their efforts, after Barca earned a 5-2 win.
How can I watch it?
As part of LaLigaTV’s coverage, viewers can catch all the action by subscribing to the channel from £5.99 per month, or £11.99 per month if bought in a package with the Premier Sports channels.
There’s good news for Sky subscribers, who can stream all content in HD providing they’re signed up to either service.
Luis Suarez is set to miss the occasion as he begins his recovery from a knee operation, while Ousmane Dembele is also sidelined.
Valencia have Dani Parejo out through suspension, after he was sent off in their last league outing away at Mallorca.
Rodrigo is also ruled out with a knee injury, while Manu Vallejo is yet to return from an ankle sprain picked up last month.
Valencia – 15/4
Barcelona – 4/6
Draw – 16/5
*All odds supplied by thepools.com