He will give evidence on the Advanced Research & Invention Agency (Aria) that he is seen as being the architect of, and has raised concerns of a lack of transparency.
The committee is chaired by Tory MP Greg Clark, the former cabinet minister against whom Mr Cummings allegedly launched a foul-mouthed tirade against in 2019, ahead of a key Brexit vote.
Experts will be given £800 million of funding to identify and fund research involving “high-risk, high-reward” science and will have independence from the Government.
Mr Cummings’ appearance before MPs will be followed by that of Business Secretary Kwasi Kwarteng who is setting up the agency.