MPs are set to debate the petition, signed by more than six million people, calling on the government to halt the Brexit process.
The Revoke Article 50 petition, due to be debated by MPs on Monday, is the best-supported proposal in the history of the House of Commons and government’s e-petitions website.
It calls for the revocation of the Article 50 letter informing the European Council of the UK’s intention to leave.
The voting will not take place until after the latest round of voting tonight in which MPs will attempt to steer the course of Brexit.
The Article 50 letter can be withdrawn by the UK unilaterally, without the need for EU agreement, leaving Britain free to continue as a member on its current terms.
The petition quickly passed the 100,000-signature threshold needed for it to be debated in Parliament, with the official committee revealing nearly 2,000 signatures were being completed every minute at one point.
A 2016 petition calling for a second EU referendum should the winning vote and turnout not reach a certain threshold had been the most signed petition, at almost 4.2 million.
The Revoke Article 50 petition also surpassed another proposal which sought to prevent Donald Trump from making a state visit to the UK, which had 1.9 million sign-ups.
It is set to be debated from 4.30pm in Westminster Hall.
Reporting by Press Association.